What is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell, essential for energy metabolism, DNA repair, and cellular signaling. NAD+ levels decline significantly with age, and this decline has been linked to reduced cellular energy production and increased susceptibility to age-related conditions.
At Calabasas Longevity, NAD+ is available as a compounded injectable — physician-prescribed and sourced from a licensed US 503A compounding pharmacy. Injectable NAD+ delivers the compound directly into the bloodstream, bypassing digestive breakdown.
Who typically explores this program
- Individuals seeking energy and cognitive clarity support
- Clients with low or inconsistent vitality and mental sharpness
- Busy professionals dealing with high stress and fatigue
- Those interested in longevity and cellular health optimization
Why pre-mixed matters. Most peptides sourced online arrive as lyophilized powder requiring reconstitution with bacteriostatic water — introducing contamination risk and dosing variability. Our compounded peptides arrive ready to inject, prepared under pharmaceutical-grade conditions by a licensed 503A pharmacy. Same compound. Dramatically higher safety standard.
Mechanisms of action
NAD+ serves as a critical coenzyme in cellular respiration, enabling mitochondria to convert nutrients into ATP — the cell's primary energy currency. It also activates sirtuins (longevity-associated proteins) and PARP enzymes involved in DNA repair.
NAD+ is a naturally occurring coenzyme involved in normal cellular processes. It may positively affect energy, metabolism, and other markers of biological aging.
Research context
- Extensive research on NAD+ decline with aging and its metabolic consequences
- Studies examining sirtuin activation and DNA repair pathway support
- Clinical interest in cognitive and neuroprotective effects
- Injectable delivery studied for superior bioavailability vs oral precursors
Important context. NAD+ is one of the most extensively researched compounds in the longevity space. Injectable administration provides direct systemic delivery — distinct from oral precursors like NMN or NR which must be converted to NAD+ after absorption. All prescribing decisions are made by your physician based on your individual health history and clinical presentation. Nothing here constitutes medical advice.
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Add to your program
Select your duration and add NAD+ to your cart. Combine with other programs in one order.
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Complete your intake
You'll receive a secure intake link. A physician reviews your health history and determines clinical appropriateness.
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Pharmacy ships
If approved, your pre-mixed compounded program ships from a licensed US 503A pharmacy within 24–48 hours.
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Weekly check-ins
Ongoing care team check-ins are included. All clinical questions go directly to your physician.
Physician determination: Calabasas Longevity is a wellness membership and referral platform — not a medical practice. All prescribing decisions are made independently by licensed physicians. We cannot guarantee a prescription will be issued. A full refund is provided if your physician does not approve your program.
